Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma

Figure 4 Expression levels of liver fatty acid-binding protein and glutamine synthetase mRNA in human hepatocellular carcinoma and cholangiocarcinoma cell lines. A: Among six hepatocellular carcinoma (HCC) cell lines examined, HepG2, HuH7, PLC, and HuH6 showed higher expression of liver fatty acid-binding protein (L-FABP). However, Li-7 and HLF showed lower expression of L-FABP. In particular, L-FABP expression was almost undetectable in HLF. Expression levels of L-FABP were very low in two CC cell lines examined (HuCCT1 and RBE); B: No obvious correlation was observed between L-FABP and glutamine synthetase expression in HCC cell lines.