T3-induced liver AMP-activated protein kinase signaling: Redox dependency and upregulation of downstream targets

Figure 3 T₃-induced changes in liver AMPK-dependent targets related to fatty acid oxidation. mRNA and protein levels of CPT-1α (A), ACOX1 (B), and ACOT2 (C), and circulating levels of β-hydroxybutyrate (D). Values shown are means ± SEM (n = 3-5). Statistical significance was performed by Student,s t-test for unpaired data (P < 0.05). AMPK: AMP-activated protein kinase; ACOT2: Acyl-CoA thioesterase 2; ACOX1: Acyl-CoA oxidase 1; CPT-1α: Carnitine palmitolytransferase-1α.