Effects of laparoscopic cholecystectomy on lung function: A systematic review

Table 4 Median percentage and interquartile range of preoperative values in forced vital capacity, forced expiratory volume in one second, and Maximal-mid expiratory flow rate variables 24 h¹ after laparoscopic and open cholecystectomies

Variables	Studies (n)	% of preoperative value [Median (IQR)]		P value
		LC	OC
FVC (L)	21	77.6 (73.0, 80.0)	55.4 (50.0, 64.0)	< 0.001
FEV1 (L)	19	76.0 (72.3, 81.0)	52.5 (50.0, 56.7)	< 0.001
FEF25%-75% (L/s)	8	78.8 (68.8, 80.9)	60.0 (36.1, 66.1)	0.005

¹One study reported values at 8 h and four studies reported values at 48 h after operation. FVC: Forced vital capacity (L); FEV₁: Forced expiratory volume in one second (L); FEF_25%-75%: Maximal-mid expiratory flow rate (L/s).