Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma

Table 3 Relation between liver fatty acid-binding protein expression and clinical features n (%)

Characteristics	Tumor size ≤2 cm		P value	Tumor size > 2 cm		P value	Total		P value
	L-FABP negative n = 11	L-FABP positive n = 74		L-FABP negative n = 5	L-FABP positive n = 56		L-FABP negative n = 16	L-FABP positive n = 130
Age	71.3 ± 7.6	63.4 ± 9.3	0.009b	54.6 ± 10.8	64.8 ± 10.7	0.044a	66.0 ± 11.5	64.0 ± 9.9	0.462
Gender			0.729			0.320			0.771
Male	7 (63.6)	52 (70.3)		5 (100)	41 (73.2)		12 (75.0)	93 (71.5)
Female	4 (36.4)	22 (29.7)		0 (0)	15 (26.8)		4 (25.0)	37 (28.5)
Viral infection
HBV	3 (27.3)	16 (21.6)	0.465	2 (40.0)	11 (19.6)	0.286	5 (31.3)	27 (20.8)	0.253
HCV	7 (63.6)	50 (67.6)	0.732	3 (60.0)	38 (67.9)	0.806	10 (62.5)	88 (67.7)	0.761
NonB nonC	1 (9.1)	8 (10.8)	0.671	0 (0)	7 (12.5)	0.531	1 (6.2)	15 (11.5)	0.451
Child-Pugh classification			0.499			0.540			0.343
A	11 (100)	71 (95.9)		5 (100)	52 (92.9)		16 (100)	123 (94.6)
B	0 (0)	3 (4.1)		0 (0)	4 (7.1)		0 (0)	7 (5.4)
C	0 (0)	0 (0)		0 (0)	0 (0)		0 (0)	0 (0)

^aP < 0.05, 54.6 ± 10.8 years vs 64.8 ± 10.7 years;

^bP < 0.01, 71.3 ± 7.6 years vs 63.4 ± 9.3 years. L-FABP: Liver fatty acid-binding protein; HBV: Hepatitis B virus; HCV: Hepatitis C virus.