Cytokine production in patients with cirrhosis and TLR4 polymorphisms

Table 4 Increment in cytokine production expressed as stimulated/spontaneous production fold change in patients with cirrhosis and TLR4 polymorphisms and wild-type patients

	Polymorphisms (n = 9)	Wild-type (n = 10)	P value
Increment TNF-α after LPS	5.3 (1.0-17.4)	3.8 (1.1-17.0)	0.280
Increment TNF-α after LTA	6.5 (1.2-14.4)	2.7 (0.2-5.1)	0.040
Increment IL-6 after LPS	26.0 (14.7-189.9)	3.3 (1.1-17.0)	< 0.001
Increment IL-6 after LTA	35.2 (15.4-183.6)	3.0 (1.2-25.6)	< 0.001
Increment IL-10 after LPS	37.8 (9.3-185.1)	6.3 (0.5-143.9)	0.006
Increment IL-10 after LTA	32.0 (11.3-70.4)	3.7 (1.0-23.7)	0.002

TNF-α: Tumour necrosis factor-alpha; LPS: Lipopolysaccharide; LTA: Lipoteichoic acid; IL: Interleukin.