Observational Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 14, 2014; 20(46): 17516-17524
Published online Dec 14, 2014. doi: 10.3748/wjg.v20.i46.17516
Table 3 Spontaneous and stimulated cytokine production by peripheral blood cells in healthy donors and all patients with cirrhosis
Healthy donors (n = 5)All patients with cirrhosis (n = 19)P value
Spontaneous TNF-α (pg/mL)< 30602.4 (96.1-3920.1)0.001
TNF-α after LPS (pg/mL)1693 (1185-3709)2904 (931-5078)0.150
TNF-α after LTA (pg/mL)638.3 (49.7-1958)2440 (241-4798)0.006
Spontaneous IL-6 (pg/mL)< 101537.8 (172.0-26053.9)0.001
IL-6 after LPS (pg/mL)20493 (19499-23042)30219 (1362-32680)0.006
IL-6 after LTA (pg/mL)22157 (17390-27010)30165 (3269-32707)0.005
Spontaneous IL-10 (pg/mL)< 3043.6 (6.5-318.1)0.210
IL-10 after LPS (pg/mL)1309 (590.2-1578)939.9 (120.8-2100)0.890
IL-10 after LTA (pg/mL)499.3 (268.7-816.9)800.4 (80.72-2077)0.150