Pancreaticoduodenectomy with vascular reconstruction for adenocarcinoma of the pancreas with borderline resectability

Table 5 Univariate analyses of factors affecting survival outcomes

Factor	Median survival (mo)	P value
Median age (yr)		0.634
≤ 64 (n = 40)	22.35 ± 3.73
> 64 (n = 38)	15.84 ± 4.40
Sex		0.445
Male (n = 45)	22.35 ± 6.32
Female (n = 33)	19.26 ± 3.74
Comorbidity		0.890
No (n = 37)	20.05 ± 4.08
Yes (n = 41)	21.36 ± 4.34
Preoperative cholangitis		0.487
No (n = 76)	19.26 ± 3.54
Yes (n = 2)	21.36
Postoperative complication		0.204
No (n = 48)	23.79 ± 5.26
Yes (n = 30)	16.76 ± 4.18
International normalized ratio		0.924
≤ 1 (n = 55)	21.36 ± 2.79
> 1 (n = 15)	27.51 ± 14.53
Creatinine level (mmol/L)		0.652
≤ 79 (n = 37)	23.79 ± 4.42
> 79 (n = 36)	13.90 ± 2.98
Total bilirubin level ( mmol/L)		0.581
≤ 72 (n = 39)	22.35 ± 3.16
> 72 (n = 38)	16.66 ± 5.01
Serum albumin level (g/L)		0.419
≤ 40 (n = 44)	28.79 ± 8.12
> 40 (n = 29)	19.09 ± 3.77
Blood loss (mL)		0.284
≤ 850 (n = 36)	28.79 ± 5.84
> 850 (n = 33)	21.36 ± 4.89
Tumor Size (cm)		0.630
≤ 3 (n = 43)	16.76 ± 3.22
> 3 (n = 28)	19.09 ± 7.97
R1 resection		0.055
No (n = 59)	25.34 ± 5.32
Yes (n = 18)	13.44 ± 3.87
Lymph node metastases		0.113
No (n = 33)	28.79 ± 3.82
< 5 (n = 37)	17.12 ± 3.05
5-10 (n = 7)	11.40 ± 5.68
> 10 (n = 1)	22.18
Disease stage (AJCC staging, 7th edition)		0.036
Early (IA + IB + IC) (n = 33)	28.79 ± 5.00
Advanced (IIB + III + IV) (n = 45)	17.12 ± 3.41
Simultaneous vascular resection		0.815
Yes (n = 32)	21.36 ± 5.93
No (n = 46)	19.26 ± 3.58
Pancreatic fistula type (according to ISGPF)		0.488
No fistula + type A (n = 73)	20.05 ± 3.43
Type B + type C (n = 5)	13.90 ± 6.61

Data are presented as mean ± SE. AJCC: American Joint Committee on Cancer; ISGPF: International Study Group on Pancreatic Fistula.