Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure

doi:10.3748/wjg.v20.i46.17399

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2014; 20(46): 17399-17406
Published online Dec 14, 2014. doi: 10.3748/wjg.v20.i46.17399

Table 3 Liver cell function during hybrid bioartificial liver support system support

Indicator	0 h	24 h	48 h	72 h
ALT (IU)	25.9 ± 4.2	28.3 ± 4.9	31.0 ± 2.6	72.1 ± 10.7^a
AST (IU)	22.0 ± 3.6	27.9 ± 10.0	31.6 ± 8.0	68.3 ± 12.7^a
LDH (mmol)	0.28 ± 0.09	0.31 ± 0.10	0.41 ± 0.12	0.74 ± 0.18^a
Urea (mmol)	2.28 ± 0.24	2.02 ± 0.21	1.82 ± 0.26	1.69 ± 0.20^a
ALB (mg)	18.67 ± 2.57	17.42 ± 1.70	14.86 ± 1.47	13.58 ± 1.61^a

^aP < 0.05 vs 0 h. ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; LDH: Lactate dehydrogenase.

Citation: Zhang Z, Zhao YC, Cheng Y, Jian GD, Pan MX, Gao Y. Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure. World J Gastroenterol 2014; 20(46): 17399-17406
URL: https://www.wjgnet.com/1007-9327/full/v20/i46/17399.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i46.17399