Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure

Table 1 Serum biochemistry with D-galactosamine administration (n = 15)

Indicators	48 h before administration	48 h after administration	P
ALT (U/L)	28.3 ± 4.7	494.2 ± 31.9	4.09 × 10-18
Ammonia (μmol/L)	28.9 ± 3.0	149.5 ± 12.3	3.14 × 10-16
TBiL (μmol/L)	1.2 ± 0.2	16.7 ± 2.1	1.06 × 10-13
TBA (U/L)	6.0 ± 1.4	51.1 ± 7.3	2.46 × 10-13
BUN (μmol/L)	3.7 ± 0.9	6.2 ± 0.9	2.96 × 10-6
Cr (μmol/L)	76.7 ± 5.7	133.5 ± 6.2	1.66 × 10-12
ALB (g/L)	41.3 ± 1.6	37.3 ± 0.6	5.86 × 10-8
Fischer index	3.2 ± 0.2	2.2 ± 0.1	1.49 × 10-11

ALB: Albumin; ALT: Alanine aminotransferase; BUN: Blood urea nitrogen; Cr: Creatinine; TBA: Total bile acid; TBiL: Total bilirubin.