Clostridium difficile infection aggravates colitis in interleukin 10-deficient mice

Figure 4 Histopathologic examination of the colonic tissue (× 100). Hematoxylin and eosin staining of colon tissues from A: Wild type (WT); B: WT challenged with Clostridium difficile (C. difficile); C: Interleukin 10-deficient (IL-10^-/-); D: IL-10^-/- challenged with C. difficile; E: Quantification of colitis severity. Error bars indicate standard error of the mean; ^aP < 0.05 vs untreated.