Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer

Figure 7 Tumor necrosis factor receptor-associated protein 1 expression is increased with oxidative damage in colon cancer cells. A: HT29 cells were treated with the indicated concentrations of H₂O₂ for 24 h and protein carbonyls were detected using enzyme-linked immunosorbent assay; B: Up-regulation of anti-apoptotic proteins following H₂O₂ treatment detected by quantitative proteomics; C: Viability assay of HT29 cells following exposure to increasing amounts of H₂O₂; D: Detection of activated caspase 3 following 24 h H₂O₂ treatment.