Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer

Figure 1 Tumor necrosis factor receptor-associated protein 1 staining increases with ulcerative colitis progression at both non-dysplastic and dysplastic sites. Plot depicts the average immunohistochemistry (IHC) score ± SE for rectal samples from normal controls, non-progressors, progressors at non-dysplastic rectal sites, and progressors at dysplastic sites. The number of patient is indicated. ^bP < 0.01 using Mann Whitney test vs normal controls. NP: Non-progressors; P: Progressors; LGD: Low grade dysplasia; HGD: High grade dysplasia; CA: Cancer; TRAP1: Tumor necrosis factor receptor-associated protein 1.