Alleviated mucosal and neuronal damage in a rat model of Crohn’s disease

Figure 5 Protein expression of heme oxygenase-1 (32 kDa) in the inflamed segments of the colon four (n = 4) and eight (n = 5) days after TNBS treatments, compared to the controls (n = 4) (C). Four days after the first and second treatment (1 × TNBS, 2 × TNBS) elevated heme oxygenase-1 (HO-1) protein level was detected. Than the amounts of protein in both samples declined and eight days after the first treatment it reached already the baseline level. Following the third treatment (3 × TNBS) HO-1 protein expression could not be detected at all. TNBS: 2,4,6-trinitrobenzenesulfonic acid; HO-1: Heme oxygenase-1.