Estradiol agonists inhibit human LoVo colorectal-cancer cell proliferation and migration through p53

Figure 5 17β-estradiol inhibits MMP-2/9 activity in LoVo colorectal colon cells. LoVo cells cultured in DMEM were treated with E2 (10^-8 mol/L) for 24 h, and then, the culture medium was collected. Samples were electrophoresed without reduction on 8% SDS polyacrylamide gels copolymerized with 0.1% gelatin.