Xeroderma pigmentosum group D polymorphisms and esophageal cancer susceptibility: A meta-analysis based on case-control studies

Table 3 Results of the meta-analysis for the xeroderma pigmentosum group D Lys751Gln polymorphism and esophageal cancer susceptibility

Study group	Co-dominant model						Dominant model			Recessive model			Additive model
	Lys/Gln vs Lys/Lys			Gln/Gln vs Lys/Lys			Gln/Gln+LysGln vs Lys/Lys			Gln/Gln vs Lys/Gln+Lys/Lys			(2Gln/Gln+Lys/Gln) vs 2(Lys/Gln+Gln/Gln+Lys/Lys)
	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph
Total	1.11 (0.94, 1.31)	0.20	0.01	1.31 (0.98, 1.75)	0.07	0.03	1.14 (0.96, 1.35)	0.14	0.001	1.21 (1.02, 1.43)	0.03	0.11	1.10 (0.99, 1.22)	0.10	0.02
Cancer type
ESCC	1.13 (0.89, 1.42)	0.31	0.03	1.44 (1.01, 2.06)	0.05	0.06	1.16 (0.91, 1.49)	0.23	0.01	1.26 (0.90, 1.77)	0.17	0.08	1.13 (0.94, 1.36)	0.21	0.02
EADC	1.09 (0.85, 1.40)	0.51	0.02	1.26 (1.02, 1.56)	0.03	0.05	1.11 (0.85, 1.44)	0.45	0.01	1.19 (0.98, 1.45)	0.08	0.25	1.07 (0.98, 1.18)	0.13	0.22
Ethnicity
Chinese	1.10 (0.82, 1.47)	0.53	0.02	2.49 (1.44, 4.29)	0.001	0.64	1.18 (0.88, 1.60)	0.27	0.01	2.37 (1.38, 4.10)	0.002	0.65	1.21 (0.94, 1.56)	0.15	0.02
Non-Chinese	1.12 (0.91, 1.38)	0.30	0.03	1.13 (0.82, 1.56)	0.45	0.02	1.11 (0.89, 1.39)	0.35	0.01	1.12 (0.93, 1.34)	0.23	0.14	1.06 (0.98, 1.15)	0.16	0.27

ESCC: Esophageal squamous cell carcinoma; EADC: Esophageal adenocarcinoma; Ph: P value of the Q-test for heterogeneity.