Clinical Trials Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 28, 2014; 20(44): 16726-16733
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16726
Table 3 Adverse events n (%)
Event
Death, n0
Drug Discontinuation due to AE6 (10)
Dose Modification due to AE8 (14)
Any life-threatening adverse event, n0
Any serious adverse event2 (4)
Hematologic event Reduced neutrophil count < 750 per mm3 < 500 per mm314 (25) 8 (15)
Mean change in hemoglobin from baseline (g/dL)
At wk 12-1.2
At wk 24-2.2
At wk 48-3.3
Erythropoietin use20 (35)
Transfusion1 (1.8)
Common adverse event
Nausea24 (43)
Anemia23 (41)
Dysgeusia20 (36)
Fatigue18 (32)
Rash6 (11)