Retrospective Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 28, 2014; 20(44): 16714-16720
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16714
Table 4 Univariate and multivariate analyses of variables predictive of severe fibrosis
VariableSevere fibrosis
P value
Yes (n = 27)No (n = 51)Univariate analysisMultivariate analysis
Gender (male/female)23/4Nov-400.474
Age (yr)66.5 ± 10.066.8 ± 10.50.950
HBs-Ag (+/-)10/1716/350.616
HCV-Ab (+/-)10/1711/400.145
Alcohol abuse (+/-)2/258/430.301
NASH (+/-)4/2310/410.602
Platelets (× 104/mm3)12.7 ± 3.918.7 ± 7.4< 0.0010.096
Prothrombin time (INR)1.09 ± 0.121.03 ± 0.100.0320.223
Albumin (g/dL)4.0 ± 0.64.1 ± 0.60.388
Total bilirubin (mg/dL)0.9 ± 0.30.7 ± 0.30.0010.354
Cholinesterase (U/L)234 ± 75255 ± 680.229
Tumor size (cm)3.5 ± 1.65.7 ± 4.20.0420.137
Tumor number1.1 ± 0.41.2 ± 0.60.543
Tumor vascular invasion (+/-)5/2216/350.226
MELD score5.8 ± 1.15.1 ± 1.20.009
CTP score5.3 ± 0.65.2 ± 0.40.685
ICG R15 (%)14.3 ± 6.110.2 ± 5.50.0190.183
LHL 150.901 ± 0.0440.935 ± 0.0240.0420.041
HH 150.648 ± 0.0680.556 ± 0.0670.0040.053
HC263.3 ± 90.4381.1 ± 96.7< 0.0010.030