Insulin-like growth factor receptor-1 overexpression is associated with poor response of rectal cancers to radiotherapy

Figure 3 Insulin-like growth factor receptor-1 immunostaining in the post-radiation rectal specimens. Regardless of radiosensitivity, strong cytoplasmic immunostaining (left panel) was often seen in the post-radiation remaining cancer cells, fibrosis was seen around the remaining tumor glandular tubes (right panel).