Gut microbiota and metabolic syndrome

doi:10.3748/wjg.v20.i43.16079

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Nov 21, 2014; 20(43): 16079-16094
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16079

Table 5 Studies conducted on humans showing effects of prebiotics on metabolic disorders

Studied subject	Prebiotic	Duration of treatment	Effects	Ref.
Healthy men and women	OFS	2 wk	↓Food and energy intake, hunger	[132]
Healthy men and women	OFS	2 wk	↑satiety	[132]
Healthy humans	GOS	12 wk	Significant ↑Bifidobacterium	[133]
Obese women	Inulin-type fructans	3 mo	↑Bifidobacterium and Faecalibacterium prausnitzii	[134]
Obese women	Inulin-type fructans	3 mo	↓Circulating LPS, Bacteroides, Propionibacterium	[134]
Obese-dyslipidemic women	Yacon syrup (containing OFS)	120 d	↓Body weight, BMI, waist circumference, serum LDL cholesterol levels	[135]
Overweight and obese adults	OFS	12 wk	↓Body weight, ghrelin, calories intake, serum glucose, insulin	[136]
Overweight and obese adults	OFS	12 wk	↑peptide YY	[136]

OFS: Oligofructose; GOS; Galactooligosaccharides; LPS: Lipopolysaccharides; BMI: Body mass index; LDL: Low-density lipoprotein.

Citation: Festi D, Schiumerini R, Eusebi LH, Marasco G, Taddia M, Colecchia A. Gut microbiota and metabolic syndrome. World J Gastroenterol 2014; 20(43): 16079-16094
URL: https://www.wjgnet.com/1007-9327/full/v20/i43/16079.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i43.16079