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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 14, 2014; 20(42): 15703-15714
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15703
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15703
Figure 3 Changes in hepatofibrosis-associated cytokines in protein and gene expression.
Rats were orally administered 30% alcohol (10 mL/kg) with or without Chunggan extract (CGX; 100 or 200 mg/kg) for 4 wk. The levels of transforming growth factor-beta (TGF-β), platelet-derived growth factor-BB (PDGF-BB), connective tissue growth factor (CTGF), and interferon-gamma (IFN-γ) were determined in liver homogenates by enzyme-linked immunosorbent assays (A), and their gene expressions were determined by real-time polymerase chain reactions (B). Data are expressed as means ± SD (n = 6-9). aP < 0.05 vs normal group, bP < 0.01 vs normal group, cP < 0.05 vs control group, dP < 0.01 vs control group. 1Only TGF-β was expressed as ng/100 μg protein. Others were according to the mg/protein, but TGF-β1 was only according to the 100 μg/mg protein.
- Citation: Kim HG, Kim JM, Han JM, Lee JS, Choi MK, Lee DS, Park YH, Son CG. Chunggan extract, a traditional herbal formula, ameliorated alcohol-induced hepatic injury in rat model. World J Gastroenterol 2014; 20(42): 15703-15714
- URL: https://www.wjgnet.com/1007-9327/full/v20/i42/15703.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i42.15703