Mechanism of gastrointestinal abnormal motor activity induced by cisplatin in conscious dogs

Figure 7 Numbers of emetic episodes in dogs receiving cisplatin alone (control, n = 10), kytril (0. 05 mg/kg, intravenous administration, n = 6) alone, and vagotomy (the normal intact dog group with resection of the vagus nerve; n = 4). Each bar represents mean ± SE. Significant differences were detected among the control group, granisetron (kytril) group, and normal intact dog group with resection of the vagus nerve (NDRVN). Control, open bar; i.v., hatched line; RNG, filled bar. ^aP < 0.05 vs control. i.v.: Intravenous administration.