Mechanism of gastrointestinal abnormal motor activity induced by cisplatin in conscious dogs

Figure 1 Interdigestive motor activity observed after intravenous administration of cisplatin (1. 2 mg/kg). A: Interdigestive motor activity was observed in the ND (n = 10); B: From approximately 3 to 4 h after the intravenous administration of cisplatin, the ND exhibited retropropagation of gastrointestinal motor activity from jejunum 2 to the gastric body, accompanied by emesis. ND: Normal intact dog group; i.v.: Intravenous administration.