Can composite performance measures predict survival of patients with colorectal cancer?

Table 5 Associations between composite performance score and five-year survival by multivariate Cox proportional hazards model

Cohort	Survival	Method
		All-or-none			70% standard			Equal weight			AHP			PCA
		HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value
1	OS	0.88	0.45-1.73	NS	0.76	0.59-0.98	0.032	0.32	0.14-0.74	0.007	0.32	0.14-0.73	0.007	0.85	0.78-0.92	< 0.001
	DSS	0.93	0.40-2.20	NS	0.69	0.52-0.91	0.009	0.30	0.12-0.79	0.014	0.28	0.11-0.70	0.006	0.85	0.77-0.95	0.002
	DFS	0.93	0.49-1.80	NS	0.78	0.61-1.01	0.057	0.40	0.17-0.92	0.031	0.36	0.16-0.80	0.013	0.87	0.79-0.95	0.002
2	OS		NA		0.92	0.73-1.17	NS	0.42	0.16-1.08	NS	0.39	0.15-0.98	0.045	0.92	0.83-1.03	NS
	DSS		NA		0.88	0.69-1.13	NS	0.35	0.13-0.94	0.038	0.31	0.12-0.81	0.017	0.90	0.81-1.01	NS
	DFS		NA		0.96	0.76-1.21	NS	0.48	0.19-1.23	NS	0.47	0.19-1.18	NS	0.95	0.83-1.03	NS
3	OS	1.07	0.54-2.13	NS	0.93	0.75-1.16	NS	0.07	0.34-1.46	NS	0.72	0.35-1.49	NS	0.98	0.89-1.08	NS
	DSS	1.33	0.60-2.92	NS	0.9	0.81-1.01	NS	0.61	0.28-1.34	NS	0.66	0.30-1.43	NS	1.00	0.89-1.11	NS
	DFS	1.13	0.58-2.19	NS	0.95	0.75-1.16	NS	0.73	0.35-1.50	NS	0.76	0.37-1.55	NS	0.99	0.90-1.08	NS

Cohort 1: Colon cancer patients stage < III; Cohort 2: Colon cancer patients stage III; Cohort 3: Rectal cancer patients. AHP: Analytic hierarchy process; DFS: Disease-free survival; DSS: Disease-specific survival; NA: Not applicable; OS: Overall survival; PCA: Principal component analysis.