Covert hepatic encephalopathy: Agreement and predictive validity of different indices

Table 4 Electroencephalographic, psychometric and psychophysic indices in four patients who were studied in different conditions over time

Patient	Condition	Time	EEG					Psychometry		CFF
			MDF (Hz)	δ	θ	α	β	PHES	MPZS	(Hz)
1 male 55, B7, MELD 11	Baseline	0	10.8	8%	19%	49%	24%	5	1.6	41
1	Post-TIPS, overt grade I	+ 11 mo	9.6	3%	34%	49%	14%	5	1.6	49
1	Post-TIPS, treated	+ 19 mo	10.5	3%	15%	64%	18%	2	0.9	46
1	Post-TIPS, treated	+ 23 mo	11.5	4%	11%	59%	27%	4	1.2	46
2 male 70, A6, MELD 9	Post-TIPS, overt grade I	0	7.9	7%	64%	20%	9%	0	-0.2	46
2	Post-TIPS, treated	+ 18 wk	10.7	10%	18%	44%	28%	-1	-0.1	39
3 male 63, B9, MELD 14	Overt grade II	0	4.8	42%	50%	6%	2%	-6	-1.8	42
3	Treated	+ 11 wk	8.2	4%	67%	21%	7%	-1	-0.5	57
4 male 69, B7, MELD 9	Overt grade II	0	5.4	45%	38%	10%	7%	-9	-2.4	37
4	Treated	+ 6 wk	10.8	4%	21%	51%	24%	-3	-0.7	39

HE: Hepatic encephalopathy; EEG: Electroencephalography; CFF: Critical flicker frequency; MDF: Mean dominant frequency; PHES: Psychometric hepatic encephalopathy score; MPZS: Mean psychometric Z score; TIPS: Transjugular intrahepatic portosystemic shunt.