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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 14, 2014; 20(42): 15499-15517
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15499
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15499
Table 2 Circulatory changes in specific vascular beds in cirrhosis
Systemic circulation |
Plasma volume ↑ |
Total blood volume ↑ |
Non-central blood volume ↑ |
Central and arterial blood volume ↓ (→) |
Cardiac output ↑ |
Arterial blood pressure ↓ (→) |
Heart rate ↑ |
Systemic vascular resistance ↓ |
Arterial and total vascular compliance ↑ |
Heart |
Left atrial volume ↑ |
Left ventricular volume → (↑) |
Right atrial volume →↑↓ |
Right ventricular volume →↑↓ |
Right atrial pressure →↑ |
Right ventricular end diastolic pressure → |
Pulmonary artery pressure →↑ |
Left ventricular end diastolic pressure → |
Hepatic and splanchnic circulation |
Hepatic blood flow ↓→ (↑) |
Hepatic venous pressure gradient ↑ |
Postsinusoidal resistance ↑ |
Renal circulation |
Renal blood flow ↓ |
Glomerular filtration rate ↓→ |
Pulmonary circulation |
Pulmonary blood flow ↑ |
Pulmonary vascular resistance ↓ (↑)1 |
Cutaneous and skeletal muscle circulation |
Skeletal muscular blood flow ↑→↓ |
Cutaneous blood flow ↑→↓ |
- Citation: Møller S, Henriksen JH, Bendtsen F. Extrahepatic complications to cirrhosis and portal hypertension: Haemodynamic and homeostatic aspects. World J Gastroenterol 2014; 20(42): 15499-15517
- URL: https://www.wjgnet.com/1007-9327/full/v20/i42/15499.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i42.15499