Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury

Figure 2 Effects of diazoxide on liver mitochondrial oxidation and phosphorylation activities in liver ischemia/reperfusion. Control group consisted of animals submitted to operative manipulation. A: Respiratory control rate (RCR); B: State 3 respiration (S3); C: ADP/O ratio. Groups of animals submitted to liver ischemia/reperfusion were treated with normal saline (Saline group) or diazoxide (Diazoxide group) 15 min prior reperfusion. Data are expressed as mean ± SEM of 6 animals per group. ^aP < 0.05 vs Control group. CONTR: Control group; SAL: Saline group; DIAZ: Diazoxide group.