Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury

Figure 1 Effects of diazoxide on serum activities. Aspartate aminotransferase (AST) (A) and alanine aminotransferase (ALT) (B) 4 and 24 h after hepatic reperfusion. Control group consisted of animals submitted to operative manipulation. Groups of animals submitted to liver ischemia/reperfusion were treated with normal saline (Saline group) or diazoxide (Diazoxide group) 15 min prior reperfusion. Data are expressed as mean ± SEM of 10 animals per group. ^a,cP < 0.05 vs Control group. CONTR: Control group; SAL: Saline group; DIAZ: Diazoxide group.