Consumption of garlic and risk of colorectal cancer: An updated meta-analysis of prospective studies

Table 2 Subgroup analyses of garlic consumption and risk of colorectal cancer

Subgroup	RC garlic intake					Garlic supplement intake
	No. of studies1	Relative risk(95%CI)	Q-test	I2(%)	Egger’s test	No. of studies	Relative risk(95%CI)	Q-test	I2(%)	Egger’s test
Colorectal cancer	4	1.07 (0.95-1.19)	0.66	0.0	0.50	5	1.12 (0.96-1.31)	0.11	46.9	0.61
Male	2	1.18 (0.99-1.41)	0.28	15.7	NA	3	1.24 (0.96-1.59)	0.31	13.6	0.75
Female	3	1.04 (0.80-1.34)	0.07	62.1	0.55	3	0.85 (0.64-1.11)	0.39	0.0	0.95
Colon cancer	4	1.07 (0.94-1.21)	0.63	0.0	0.23	3	1.01 (0.77-1.32)	0.15	47.3	0.58
Male	2	1.18 (0.98-1.43)	0.61	0.0	NA	2	1.30 (0.91-1.85)	0.39	0.0	NA
Female	3	1.01 (0.86-1.19)	0.10	56.5	0.49	2	0.73 (0.50-1.09)	0.85	0.0	NA
Rectal cancer	3	1.02 (0.90-1.17)	0.93	0.0	0.59	3	1.17 (0.74-1.83)	0.41	0.0	0.31
Male	2	1.13 (0.86-1.49)	0.26	22.5	NA	2	1.59 (0.94-2.69)	0.85	0.0	NA
Female	2	0.97 (0.67-1.40)	0.46	0.0	NA	2	0.69 (0.32-1.48)	1.00	0.0	NA
Proximal colon cancer	3	1.06 (0.88-1.28)	0.53	0.0	0.04	2	0.78 (0.51-1.21)	0.77	0.0	NA
Distal colon cancer	3	1.12 (0.87-1.45)	0.55	0.0	0.89	2	1.15 (0.43-3.12)	0.04	75.4	NA

¹Data from NHS and HPFS (both conducted by Meng et al[2]. in 2013) were counted as different studies. RC: Raw and cooked.