Fish consumption and risk of gastrointestinal cancers: A meta-analysis of cohort studies

Table 2 Summary relative risk for various cancer sites or different geographical regions and incremental estimates for 20-g/d increment of fish consumption

Cancer sitesregions		CorrespondingRR (95%CI) for cancer	Heterogeneity test			RR for 20 g/dIncrement of fish
			Q value	P value	I2(%)
	Total	0.93 (0.88-0.98)	80.14	0.000	67.6	0.98 (0.96-1.01)
	Total male	0.95 (0.87-1.02)	13.97	0.082	42.8
	Total female	0.96 (0.89-1.03)	27.60	0.001	71.0
	Low consumption	0.94 (0.89-0.99)	50.29	0.003	48.3
	High consumption	0.91 (0.84-0.97)	70.27	0.000	63.0
Colorectum	Total	0.93 (0.87-0.99)	53.85	0.000	64.7	0.99 (0.97-1.01)
	Low consumption	0.95 (0.91-0.98)	13.12	0.832	0.0
	High consumption	0.91 (0.82-0.99)	55.50	0.000	65.8
Colon	Total	0.95 (0.91-0.98)	10.53	0.160	33.5
	Low consumption	0.97 (0.92-1.02)	3.15	0.871	0.0
	High consumption	0.90 (0.81-0.99)	12.65	0.081	44.7
Rectum	Total	0.85 (0.75-0.95)	16.66	0.020	58.0
	Low consumption	0.86 (0.80-0.93)	3.32	0.853	0.0
	High consumption	0.85 (0.70-0.99)	17.53	0.014	60.1
Esophagus	Total	0.91 (0.83-0.99)	2.43	0.297	17.6
	Low consumption	0.90 (0.79-1.02)	0.43	0.807	0.0
	High consumption	0.95 (0.73-1.17)	4.71	0.095	57.5
Stomach	Total	1.04 (0.97-1.10)	5.94	0.430	0.0	1.03 (1.00-1.05)
	Low consumption	1.02 (0.94-1.11)	6.75	0.344	11.1
	High consumption	1.06 (0.96-1.17)	3.06	0.802	0.0
Liver	Total	0.71 (0.38-1.03)	29.04	0.000	93.1	0.89 (0.84-0.94)
	Low consumption	0.73 (0.34-1.13)	23.75	0.000	91.6
	High consumption	0.71 (0.48-0.95)	6.60	0.037	69.7
Pancreas	Total	1.07 (0.96-1.17)	19.49	0.012	59.0	1.02 (0.96-1.08)
	Low consumption	1.05 (0.93-1.17)	15.38	0.052	48.0
	High consumption	1.04 (0.96-1.11)	8.73	0.366	8.4
Asia		0.98 (0.81-1.15)	49.49	0.000	87.9
Europe		0.94 (0.86-1.01)	16.86	0.051	46.6
North America		0.88 (0.81-0.97)	19.73	0.011	59.5