Safety of hepatectomy for elderly patients with hepatocellular carcinoma

Table 4 Outcome of hepatectomy for elderly hepatocellular carcinoma patients

Ref.	Year	Country	Age	Number of patients		Mortality rate (%)		Morbidity rate (%)		OS at 5 years (%)
				Y	E	Y	E	Y	E	Y	E
Takenaka et al[9]	1994	Japan	70	229	39	1	5	50	51	51.6	75.9
Yamamoto et al[62]	1997	Japan	70	40	7	5	42.91	NA	NA	NA	NA
Poon et al[10]	1999	China	70	299	31	6	10	40	48	51	58
Wu et al[23]	1999	Taiwan	80	239	21	2.1	0	15.5	14.3	59.3	40.9
Hanazaki et al[11]	2001	Japan	70	283	103	6	9.7	23.3	28.2	40	42.2
Yeh et al[12]	2004	Taiwan	70	398	34	7.7	10.5	NA	NA	32.1	39.6
Ferrero et al[13]	2005	Italy	70	177	64	9.6	3.1	42.4	23.41	32.3	48.6
Zhou et al[61]	2006	China	65	125	54	2.4	0	NA	NA	38.6	50.1
Kondo et al[14]	2008	Japan	70	210	109	2.9	3.7	43.8	41.3	NA	NA
Kaibori et al[15]	2009	Japan	70	333	155	4	3	19	18	57.3	54.6
Oishi et al[16]	2009	Japan	75	502	64	1	2	19	22	64	58
Huang et al[33]	2009	China	70	268	67	1.1	1.5	4.5	9	31.4	43.21
Mirici-Cappa et al[34]	2010	Italy	70	142	43	NA	NA	NA	NA	32.4	44.8
Tsujita et al[17]	2010	Japan	75	77	23	1	0	NA	NA	832	702
Portolani et al[35]	2011	Italy	70	276	175	4.3	3.4	16.7	16	NA	NA
Yamada et al[24]	2012	Japan	80	267	11	0	0	3.3 (LF)	0 (LF)	43	26
Tsujita et al[25]	2012	Japan	80	385	23	0.8	4.3	NA	NA	84.8	95.7
Nishikawa et al[19]	2013	Japan	75	206	92	NA	NA	15.5	16.3	64.4	43
Hirokawa et al[59]	2013	Japan	70	120	100	2	2	35	32	64	56
Ide et al[20]	2013	Japan	75	192	64	3.1	3.1	29	33	68	59
Ueno et al[21]	2013	Japan	75	186	66	1	0	19	26	NA	NA
Taniai et al[64]	2013	Japan	75	353	63	2.8	6.3	22.9	30.2	46.6	40.2
Wang et al[63]	2014	China	70	152	56	1.3	3.6	47.4	53.6	NA	NA

¹Represents significant difference;

²Represents OS at 3 years. Y: Younger patients; E: Elderly patients; OS: Overall survival rate; NA: Not available; LF: Liver failure.