Targeted migration of mesenchymal stem cells modified with CXCR4 to acute failing liver improves liver regeneration

Figure 2 Chemokine CXC receptor 4 gene enhances mesenchymal stem cells migration depending on stromal cell-derived factor-1α. A: Stromal cell-derived factor (SDF)-1α expression in acute liver failure (ALF). Values are mean ± SD, n = 6 for each group; B: Images of transmigrated chemokine CXC receptor 4 (CXCR4)-mesenchymal stem cells (MSCs) (left) and Null-MSCs (right) in response to 50 ng/mL SDF-1α in Transwell assay; C: Average number of cells migrated in Transwell assay. Results are mean values ± SD of five different fields from four independent experiments. ^aP < 0.05 vs normal group; ^cP < 0.05 vs Null group, data are shown as mean ± SD.