Copyright
©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 28, 2014; 20(40): 14733-14746
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14733
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14733
Table 4 Meta-analyses of adjuvant chemoradiotherapy in pancreatic cancer
| Survival (95%CI) | |||||
| Year published | Author | Arm (n) | Median survival (mo) | 2-yr survival | 5-year survival |
| 2005 | Stocken et al[20] | CRT | 15.8 (13.9-18.1) | 30% | 12% |
| No CRT | 15.2 (13.1-18.2) | 34% | 17% | ||
| 2008 | Butturini et al[25] | R0 Resections | |||
| CRT (188) | 15.9 (14-18.5) | 30% (23%-36%) | 10% (5%-15%) | ||
| No CRT (183) | 15.8 (13.4-20.1) | 38% (31%-45%) | 20% (13%-26%) | ||
| R1 Resections | |||||
| CRT (53) | 14.7 (11.5-20.5) | 30% (17%-42%) | 18% (7%-29%) | ||
| No CRT (53) | 11.2 (9.4-16.7) | 19% (8%-31%) | 8% (0%-16%) | ||
| 2013 | Liao et al[26] | Hazard ratio for death (95%CI) | |||
| Chemoradiation (169) | 0.91 (0.55-1.46) | ||||
| Observation (670) | |||||
| Chemoradiation + 5-FU (323) | 0.87 (0.27-2.69) | ||||
| 5-FU (876) | |||||
| Chemoradiation + 5-FU (323) | 0.59 (0.19-1.74) | ||||
| Chemoradiation (169) | |||||
| Chemoradiation + gemcitabine (221) | 0.82 (0.4-1.71) | ||||
| Chemoradiation + 5-FU (323) | |||||
- Citation: Jones OP, Melling JD, Ghaneh P. Adjuvant therapy in pancreatic cancer. World J Gastroenterol 2014; 20(40): 14733-14746
- URL: https://www.wjgnet.com/1007-9327/full/v20/i40/14733.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i40.14733