Chemotherapy-related reactivation of hepatitis B infection: Updates in 2013

doi:10.3748/wjg.v20.i40.14581

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Oct 28, 2014 (publication date) through Jan 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2014; 20(40): 14581-14588
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14581

Table 1 Risk factors for anticancer chemotherapy-related hepatitis B virus reactivation

Categories	Risk factors	Ref.
Host factors	Male gender Young age Elevated baseline ALT	[8] [8] [63]
Tumor- or treatment-related factors	Lymphoma Hematologic malignancies Brease cancer Glucocorticoid use Anthracycline use Rituximab-based regimen Hematopoietic stem cell transplantation	[6,8] [8,64] [6] [6,16] [6] [17,29] [65]
Viral factors	High pre-chemotherapy viral load Positive HBeAg Presence of precore mutant Negative or low titer of HBsAb (in case of occult/past infection)	[66] [8,67] [25,68] [17]

ALT: Alanine aminotransferase; HBeAg: Hepatitis B e antigen; HBsAb: Hepatitis B surface antibody.

Citation: Kim HY, Kim W. Chemotherapy-related reactivation of hepatitis B infection: Updates in 2013. World J Gastroenterol 2014; 20(40): 14581-14588
URL: https://www.wjgnet.com/1007-9327/full/v20/i40/14581.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i40.14581