Clinical management of advanced gastric cancer: The role of new molecular drugs

doi:10.3748/wjg.v20.i40.14537

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Oct 28, 2014 (publication date) through Nov 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2014; 20(40): 14537-14558
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14537

Table 5 Clinical trials with everolimus in previously treated patients with advance gastric cancer and gastro-esophageal junction cancer

Trial	Phase	Setting	Regimen	Patients (n)	OS (mo)	PFS (mo)
NCT00985192[137], 2010	II	Advanced	Eve	53	10.1	2.7
NCT00879333[138], 2013	III	Advanced	Eve + BSC	656	5.4	1.7
NCT00879333[138], 2013	III	Advanced	BSC	656	4.3	1.4
NCT01248403[139], Ongoing	III	Advanced	Eve + PTX	480	-	-
NCT01248403[139], Ongoing	III	Advanced	PTX	480	-	-

Eve: Everolimus; PTX: Paclitaxel; OS: Overall survival; PFS: Progression free survival.

Citation: Vita FD, Martino ND, Fabozzi A, Laterza MM, Ventriglia J, Savastano B, Petrillo A, Gambardella V, Sforza V, Marano L, Auricchio A, Galizia G, Ciardiello F, Orditura M. Clinical management of advanced gastric cancer: The role of new molecular drugs. World J Gastroenterol 2014; 20(40): 14537-14558
URL: https://www.wjgnet.com/1007-9327/full/v20/i40/14537.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i40.14537