Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectives

doi:10.3748/wjg.v20.i4.923

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2014; 20(4): 923-942
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.923

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Figure 6 Possible role of the interaction between CXCR4/CD133 cancer cells and SDF-1 ligands. The SDF-1 ligand secreted by carcinoma-associated fibroblasts (CAF) in tumor microenvironment interacts with CXCR4/CD133 expressing cancer cells and could drive primary tumor cells towards metastatic sites.

Citation: Fanali C, Lucchetti D, Farina M, Corbi M, Cufino V, Cittadini A, Sgambato A. Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectives. World J Gastroenterol 2014; 20(4): 923-942
URL: https://www.wjgnet.com/1007-9327/full/v20/i4/923.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i4.923