Neuroanatomy of lower gastrointestinal pain disorders

doi:10.3748/wjg.v20.i4.1005

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Jan 28, 2014 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2014; 20(4): 1005-1020
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.1005

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Figure 2 Scheme is oversimplified and limited to the cell types and mediators discussed in this review and represents a subset of cells and inflammatory mediators responsible for activation of gut sensory afferents after an initial inflammatory response. 5-HT: 5-hydroxytryptamine; BK: Bradykinin; CGRP: Calcitonin-gene-related peptide; ECC: Enterochromaffin cell; GABA: Gamma-amino butyric acid; NGF: Nerve growth factor; NO: Nitric oxide; PAR: Proteinase-activated receptor; PG: Prostaglandin; SP: Substance P; TrKA: Tyrosine receptor kinase A; TRPA1: Transient receptor potential ankyrin-1; TRPV1: Transient receptor potential vanilloid-1; P2X3: Purinergic P2X3 receptor.

Citation: Vermeulen W, Man JGD, Pelckmans PA, Winter BYD. Neuroanatomy of lower gastrointestinal pain disorders. World J Gastroenterol 2014; 20(4): 1005-1020
URL: https://www.wjgnet.com/1007-9327/full/v20/i4/1005.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i4.1005