Role of surgery and transplantation in the treatment of hepatic metastases from neuroendocrine tumor

Table 1 Comparison of outcomes

Labels	Publication year	Number of patients LR/other	5 yr OS LR/other	Median survival LR/other (mo)
Liver resection vs no Liver resection
Søreide et al[16]	1992	36/39		216/48
Chen et al[17]	1998	15/23	73%/29%	1/27
Grazi et al[7]	2000	9/19	92.6%/18.5%2
Ahmed et al[18]	2009	50/310	78%/52%	135/66
Surgery vs Ablation
Yao et al[19]	2001	16/20	70%/40%	3/32
Osborne et al[20]	2006	38 Complete and 23 palliative/53	78% and 64%/35%	50 ± 27.6/32 ± 18.9
Surgery vs Intra-arterial therapy
Mayo et al[21]	2011	339/414	74%/30%	123/34
Surgery vs Transplantation
Coppa et al[22]	2001	9/20	67%/70%	29%/53%
Surgical resection
Mayo et al[23]	2011	Resection +/- Ablation (66 simultaneous ablation)	339
Saxena et al[24]	2011	Resection +/- Ablation	74
Karabulut et al[25]	2011	Resection	27
Glazer et al[26]	2010	Resection +/- Ablation (18 Patients only RFA)	172	77.40%
Scigliano et al[27]	2009	Resection	41	79%
Fischer et al[28]	2008	Resection	118	44%
Kianmanesh et al[29]	2008	Resection	23	94%
Gomez et al[30]	2007	Resection	18	86%
Osborne et al[20]	2006	Cytoreduction	704
Musunuru et al[31]	2006	Resection +/- Ablation	13	83%5
Touzios et al[32]	2005	Resection +/- Ablation	18	72%
Sarmiento et al[2]	2003	Complete resection in 70 patients	170	61%
Elias et al[33]	2003	Resection and 36 with concurrent extrahepatic resection	47	71%
Coppa et al[22]	2001	Resection	20	67%
Grazi et al[7]	2000	Resection	19	92%6
Chen et al[17]	1998	Resection	15	73%

¹Median survival not reached during the study period;

²4 year survival;

³Median survival not reached during the study period;

⁴Mean survival;

⁵3 year survival;

⁶4-year survival.