Hepatitis B and liver transplantation: Molecular and clinical features that influence recurrence and outcome

doi:10.3748/wjg.v20.i39.14142

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2014; 20(39): 14142-14155
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14142

Table 1 Three protocols for prevention of recurrent hepatitis B virus infection after liver transplantation

HBIG-indefinite (HBIG continued for life)	HBIG 10000 IU iv during anhepatic phase;
	then 5000 IU iv daily for 5 d; followed by 800 IU im monthly indefinitely
	Plus
	ETV or TFV indefinitely
HBIG-light (HBIG for first 6 mo only)	HBIG 10000 IU iv during anhepatic phase;
	then 5000 IU iv daily for 5 d; followed by 800 IU im monthly for 6 mo
	Plus
	ETV and/or TFV indefinitely
HBIG-free (No HBIG)	ETV and/or TFV indefinitely

ETV: Entecavir; HBIG: Hepatitis B immune globulin; im: Intramuscular; iv: Intravenous; TFV: Tenofovir. The appropriate annual costs of these are set out in Table 2.

Citation: Ghaziani T, Sendi H, Shahraz S, Zamor P, Bonkovsky HL. Hepatitis B and liver transplantation: Molecular and clinical features that influence recurrence and outcome. World J Gastroenterol 2014; 20(39): 14142-14155
URL: https://www.wjgnet.com/1007-9327/full/v20/i39/14142.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i39.14142