Copyright
©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 21, 2014; 20(39): 14105-14125
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14105
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14105
Table 2 Cognitive performance in irritable bowel syndrome
Cognitive domain | Sample size:IBS/Control/Other | IBS subtype | SexMale:Female | Mean ageIBS/Control/Other | Key finding | Ref. |
Visuospatial memory | 39/40 | IBS-D = 7; IBS-C = 4; IBS-A = 28 | 6:33 (IBS) | 28/28 | Impaired performance which correlated with salivary cortisol levels | [140] |
11:29 (Control) | ||||||
40/41 | N.S. | 13:27 (IBS) | 37/43 | No group differences | [245] | |
16:25 (Control) | ||||||
Working memory | 39/40 | IBS-D = 7; IBS-C = 4; IBS-A = 28 | 6:33 (IBS) | 28/28 | No group differences | [140] |
11:29 (Control) | ||||||
40/41 | N.S. | 13:27 (IBS) | 37/43 | No group differences | [245] | |
16:25 (Control) | ||||||
Cognitive flexibility | 30/30 | IBS-D = 13; IBS-C = 13; IBS-A = 4 | 15:15 (IBS) | 21/21 | Impaired cognitive flexibility and altered frontal brain activity in IBS | [141] |
15:15 (Control) | ||||||
39/40 | IBS-D = 7; IBS-C = 4; IBS-A = 28 | 6:33 (IBS) | 28/28 | No group differences | [140] | |
11:29 (Control) | ||||||
40/41 | N.S. | 13:27 (IBS) | 37/43 | No group differences | [245] | |
16:25 (Control) | ||||||
Selective attention | 39/40 | IBS-D = 7; IBS-C = 4; IBS-A = 28 | 6:33 (IBS) | 28/28 | No group differences | [140] |
11:29 (Control) | ||||||
40/41 | N.S. | 13:27 (IBS) | 37/43 | No group differences | [245] | |
16:25 (Control) | ||||||
27/27 | N.S. | 3:24 (IBS) | 45/42 | No group differences | [246] | |
3:24 (Control) | ||||||
Reaction time | 40/41 | N.S. | 13:27 (IBS) | 37/43 | No group differences | [245] |
16:25 (Control) | ||||||
Affective attention | 15/15 | IBS-D = 6; IBS-C = 3; IBS-A = 3; Other = 3 | 4:11 (IBS) | 30/30 | Enhanced attention to GI symptom-related words | [247] |
5:10 (IBS) | ||||||
20 (Rome II Criteria)/33 | N.S. | 2:18 (IBS) | 31/27 | Enhanced attention to pain-related words | [248] | |
12:21 (Control) | ||||||
36 (Rome II Criteria)/40 (mixed organic GI disease) | N.S. | 12:24 (IBS) | 35/36 | Enhanced recognition of GI-related words | [249] | |
16:24 (mixed organic GI disease) | ||||||
Affective memory | 30 (Manning criteria)/30/28 (depressed patients)/28 (organic GI disease) | N.S. | N.S. | 36/35/38/27 (median age) | Enhanced recall of negative words compared to control and organic GI disease - no difference in comparison to depression group | [250] |
- Citation: Kennedy PJ, Cryan JF, Dinan TG, Clarke G. Irritable bowel syndrome: A microbiome-gut-brain axis disorder? World J Gastroenterol 2014; 20(39): 14105-14125
- URL: https://www.wjgnet.com/1007-9327/full/v20/i39/14105.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i39.14105