Accuracy of early detection of colorectal tumours by stool methylation markers: A meta-analysis

Figure 2 Forest plot of SFRP2 methylation in the diagnosis of colorectal cancer. A: Shows the sensitivity of SFRP2 methylation in stool samples used for colorectal carcinoma diagnosis. The point estimates of specificity from each study are shown as red squares; B: Shows the specificity of SFRP2 methylation in stool samples used for colorectal cancer diagnosis. The point estimates of specificity from each study are shown as blue squares; C: Shows the summary receiver operating characteristic curves (SROC) of SFRP2 methylation assays used for diagnosis of colorectal carcinoma. Red circles represent each study that was included in the meta-analysis. The size of each study is indicated by the size of the red circle. SROC curves summarize the overall diagnostic accuracy. Error bars indicate the 95%CI, and df indicates the degrees of freedom.