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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 14, 2014; 20(38): 13741-13755
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741
Figure 1 Human epidermal growth factor receptor 2 signaling pathways.
HER: Human epidermal growth factor receptor; BAD: Bcl-2-associated death promotor protein; Grb2: Growth factor receptor-bound protein 2; MAPK: Mitogen-activated protein kinase; MEK: Mitogen-activated protein kinase kinase 1; NF-κB: Nuclear factor κB; PI3K: Phospohoinositide 3-kinase; PKC: Protein kinase C; PLC-γ: Phospholipase C gamma 1; SOS: Son of sevenless; mTOR: Mammalian target of rapamycin; RAS: Rat sarcoma viral oncogene; RAF: Rapidly accelerated fibrosarcoma.
- Citation: Aoyagi K, Kouhuji K, Kizaki J, Isobe T, Hashimoto K, Shirouzu K. Molecular targeting to treat gastric cancer. World J Gastroenterol 2014; 20(38): 13741-13755
- URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13741.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i38.13741