Simultaneous modulated accelerated radiation therapy for esophageal cancer: A feasibility study

doi:10.3748/wjg.v20.i38.13973

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Oct 14, 2014 (publication date) through Aug 28, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Oct 14, 2014; 20(38): 13973-13980
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13973

Table 2 Averaged over ten patients dose-volume histograms parameters of organs at risk with P-value for comparison

		SMART	IMRT	3DCRT	P value
		SMART	IMRT	3DCRT	SMART vs IMRT	SMART vs 3DCRT
Cord	D_max	38.5 ± 2.0	39.5 ± 0.9	44.7 ± 0.8	0.660	0.002¹
	D_1cc	35.6 ± 2.2	36.3 ± 1.2	41.6 ± 1.6	0.266	0.000
SC-PRV	D_max	44.5 ± 1.9	47.1 ± 2.7	59.3 ± 2.2	0.010¹	0.002¹
	D_1cc	40.8 ± 2.5	42.5 ± 2.2	52.9 ± 3.8	0.027¹	0.002¹
Heart	D_mean	14.4 ± 7.5	16.2 ± 8.5	21.4 ± 11.1	0.000	0.000
	V₂₀	34.1 ± 18.9	38.1 ± 21.9	42.7 ± 22.4	0.005	0.000
	V₃₀	18.2 ± 10.0	21.8 ± 11.6	38.0 ± 21.0	0.001	0.001
	V₄₀	9.4 ± 5.7	12.2 ± 7.2	25.3 ± 16.3	0.001	0.002¹
	V₅₀	4.9 ± 3.4	7.0 ± 4.6	12.9 ± 7.6	0.001	0.000
Lung	D_mean	9.0 ± 1.7	9.9 ± 1.8	12.4 ± 2.1	0.000	0.000
	V₅	47.6 ± 9.7	50.4 ± 10.2	51.0 ± 9.9	0.000	0.017
	V₁₀	34.7 ± 7.4	37.6 ± 7.6	40.6 ± 8.1	0.000	0.002
	V₁₃	27.3 ± 5.9	30.2 ± 6.1	34.7 ± 7.3	0.000	0.000
	V₂₀	17.1 ± 4.0	20.2 ± 4.3	25.8 ± 5.0	0.000	0.000
	V₃₀	3.6 ± 1.3	4.7 ± 1.6	13.4 ± 4.8	0.000	0.000

¹By Wilcoxon matched-pair signed-rank test using exact method. SMART: Simultaneous modulated accelerated radiation therapy; IMRT: Intensity-modulated radiation therapy; 3DCRT: Three-dimensional conformal radiotherapy; SC-PRV: Spinal cord planning risk volume.

Citation: Zhang WZ, Chen JZ, Li DR, Chen ZJ, Guo H, Zhuang TT, Li DS, Zhou MZ, Chen CZ. Simultaneous modulated accelerated radiation therapy for esophageal cancer: A feasibility study. World J Gastroenterol 2014; 20(38): 13973-13980
URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13973.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i38.13973