Gastric cancer: Prevention, screening and early diagnosis

Table 2 Gastric cancer differentiation using narrow-band imaging with or without magnification

Ref.	Endoscopic technique	Differentiated-type EGC (D-EGC)	Undifferentiated-type EGC (UD-EGC)
Nakayoshi et al[161]	NBI-ME	Relatively regular fine network pattern	Relatively irregular, twisting or corkscrew pattern, with a relatively low density of microvessels
Endo et al[162]	NBI-ME	Grid network pattern with hypervascularity	Short twig or branch-like pattern with hypovascularity
Tamai et al[163]	NBI-ME describing depressed gastric adenomas vs protruding adenomas	Intramucosal carcinomas were more frequently found in depressed adenomas (reddish in color, a regular ultrafine network pattern of mucosal microvasculature) (25%) than in protruding adenomas (4.5%)
Yao et al[164]	NBI-ME	WOSa white substance within the neoplastic epithelium that may obscure the subepithelial microvascular pattern. More frequent in non-advanced neoplasia than in advanced carcinomas and that 100% of non- advanced lesions demonstrated a regular distribution of WOS
Yokoyama et al[165]	NBI-ME	Amongst the D-EGC lesions, fine-network pattern, intra-lobular loop pattern-1, intra-lobular loop pattern-2 and corkscrew pattern were observed in 15.7%, 59.6%, 24.2% and 0.5%, respectively. D-EGCs mainly exhibited fine-network pattern or intra-lobular loop pattern	In UD-EGC intra-lobular loop pattern-2 and corkscrew pattern were observed in 41.2% and 58.8%, respectively. Therefore, UD-EGCs were all classified as intra-lobular loop pattern-2 and corkscrew pattern

NBI-ME: Narrow-band imaging with or without magnification; EGC: Early gastric cancer.