Molecular targeting to treat gastric cancer

doi:10.3748/wjg.v20.i38.13741

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Oct 14, 2014 (publication date) through Feb 5, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2014; 20(38): 13741-13755
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741

Table 5 Clinical trials of everolimus

Patients	Phase	Treatment	n	OS (mo)	PFS (mo)	RR	DCR
Previously treated metastatic gastric cancer	II	Everolimus	53	10.1	2.7	0%	54.7%
Second-line treatment for advanced gastric cancer (GRANITE-1)	III	Placebo	217	4.34	1.41	2.1%	N/A
	III	Everolimus	439	5.39	1.68	4.5%	N/A

DCR: Disease control rate; N/A: Not available; OS: Overall survival; PFS: Progression-free-survival; RR: Response rate; TTP: Time to progression.

Citation: Aoyagi K, Kouhuji K, Kizaki J, Isobe T, Hashimoto K, Shirouzu K. Molecular targeting to treat gastric cancer. World J Gastroenterol 2014; 20(38): 13741-13755
URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13741.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i38.13741