Molecular targeting to treat gastric cancer

doi:10.3748/wjg.v20.i38.13741

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Oct 14, 2014 (publication date) through Jul 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2014; 20(38): 13741-13755
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741

Table 4 Clinical trial of lapatinib

Patients	Phase	Treatment	n	OS (m)	PFS (m)	RR
Second-line treatment for HER2+ advanced gastric cancer (TYTAN)	III	Paclitaxel	129	8.9	4.2	9%
	III	Paclitaxel + lapatinib	132	11.0	5.2	27%

OS: Overall survival; PFS: Progression-free-survival; RR: Response rate; HER2: Human epidermal growth factor receptor 2.

Citation: Aoyagi K, Kouhuji K, Kizaki J, Isobe T, Hashimoto K, Shirouzu K. Molecular targeting to treat gastric cancer. World J Gastroenterol 2014; 20(38): 13741-13755
URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13741.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i38.13741