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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 14, 2014; 20(38): 13741-13755
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13741
Table 3 Clinical trials of bevacizumab
Patients | Phase | Treatment | n | OS (m) | PFS (m) | TTP (m) | RR |
Metastatic or unresectable gastric and GEJ adenocarcinoma | II | Irinotecan + cisplatin + bevacizumab | 47 | 12.3 | N/A | 8.3 | 65% |
Previously untreated metastatic gastroesophageal adenocarcinoma | II | Docetaxel + fluorouracil + bevacizumab | 44 | 16.8 | 12 | N/A | 67% |
First-line treatment for advanced gastric cancer (AVAGASTA) | III | Capecitabine + cisplatin | 387 | 10.1 | 5.3 | 37.4 | N/A |
387 | 12.1 | 6.7 | 46 | N/A | |||
First-line treatment for advanced gastric cancer (AVAGASTA) | III | Capecitabine + cisplatin + bevacizumab |
- Citation: Aoyagi K, Kouhuji K, Kizaki J, Isobe T, Hashimoto K, Shirouzu K. Molecular targeting to treat gastric cancer. World J Gastroenterol 2014; 20(38): 13741-13755
- URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13741.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i38.13741