Epidermal growth factor upregulates serotonin transporter and its association with visceral hypersensitivity in irritable bowel syndrome

Figure 2 Epidermal growth factor levels in plasma and colon tissue of the visceral-sensitized rats. A: Plasma epidermal growth factor (EGF) levels were significantly lower in visceral-sensitized rats than in controls (visceral hypersensitive group rats vs control group rats, ^bP < 0.01); B: EGF levels in colon were significantly lower in visceral-sensitized rats than in controls (visceral-sensitized rats vs control rats, ^dP < 0.01). Error bars represent the mean ± SD (n = 10 in each group).