Contribution of TLR signaling to the pathogenesis of colitis-associated cancer in inflammatory bowel disease

doi:10.3748/wjg.v20.i36.12713

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Sep 28, 2014 (publication date) through Dec 1, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2014; 20(36): 12713-12721
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12713

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Figure 1 Relationship between pattern recognition receptors and tissue regeneration. In case of acute tissue injury, TLRs acts as mucosal healing factors. In the case of chronic, sustained inflammation, TLRs may promote dysregulated wound healing leading to cancer development. PRRs: Pattern recognition receptors; TLRs: Toll-like receptors; IFNs: Interferons; TGF: Transforming growth factor; PDGF: Platelet-derived growth factor.

Citation: Sipos F, Fűri I, Constantinovits M, Tulassay Z, Műzes G. Contribution of TLR signaling to the pathogenesis of colitis-associated cancer in inflammatory bowel disease. World J Gastroenterol 2014; 20(36): 12713-12721
URL: https://www.wjgnet.com/1007-9327/full/v20/i36/12713.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i36.12713