IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients

doi:10.3748/wjg.v20.i36.13146

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 36

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (5742)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-1) series, Tables (1-3) series.

Item

Count

PDF

350

WORD

261

HTML

3235

Figures (1-1)

179

Tables (1-3)

164

Sum=4189

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

886

Download

667

Sum=1553

Sep 28, 2014 (publication date) through Jul 18, 2024

Times Cited of This Article

Times Cited (18)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastroenterol. Sep 28, 2014; 20(36): 13146-13152
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13146

Table 3 Sensitivity, specificity, positive and negative predictive value of single and combined IL28B polymorphisms for achieving hepatitis C virus RNA drop ≥ 1 log at treatment week 4

IL28B polymorphisms	Sn	Sp	PPV	NPV	LR
rs8099917_TT	59%	81%	91%	36%	3.05
rs12979860_CC	29%	88%	90%	26%	2.54
rs8099917_TT or rs12979860_CC	29%	92%	93%	27%	3.82

IL: Interleukin; Sn: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; LR: Likelihood ratio.

Citation: Rosso C, Abate ML, Ciancio A, Strona S, Caviglia GP, Olivero A, Touscoz GA, Rizzetto M, Pellicano R, Smedile A. IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients. World J Gastroenterol 2014; 20(36): 13146-13152
URL: https://www.wjgnet.com/1007-9327/full/v20/i36/13146.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i36.13146