Identification of pathologic features associated with &ldquo;ulcerative colitis-like&rdquo; Crohn&rsquo;s disease

doi:10.3748/wjg.v20.i36.13139

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Sep 28, 2014 (publication date) through Oct 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2014; 20(36): 13139-13145
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13139

Table 2 Microscopic pathologic features in "ulcerative colitis-like" Crohn’s disease and "true" ulcerative colitis n (%)

Microscopic features	“UC-like” CD	“True”UC	P value
Active ileitis	7/17 (41)	0/18 (0)	< 0.05^a
Appendiceal activity	8/16 (50)	2/18 (11)	< 0.05^a
Appendiceal fibrous obliteration	1/16 (6)	5/18 (28)	0.18
Severe activity	8/17 (47)	14/18 (78)	< 0.05^a
Prominent lamina propria neutrophils	13/17 (76)	4/18 (22)	< 0.05^a
Prominent lymphoid aggregates	8/17 (47)	3/18 (17)	0.07
Prominent chronicity/architectural distortion	8/17 (47)	12/18 (67)	0.49
Prominent basal plasmacytosis	4/17 (24)	6/18 (33)	0.71
Prominent muscularis mucosa inflammation	8/17 (47)	9/18 (50)	1.00
Prominent submucosal fibrosis	3/17 (18)	3/18 (17)	1.00
Prominent thickening of muscularis mucosa	4/17 (24)	5/18 (28)	1.00
Paneth cell metaplasia	8/17 (47)	6/18 (33)	1.00

^aP < 0.05 vs control. UC: Ulcerative colitis; CD: Crohn’s disease.

Citation: James SD, Wise PE, Zuluaga-Toro T, Schwartz DA, Washington MK, Shi C. Identification of pathologic features associated with “ulcerative colitis-like” Crohn’s disease. World J Gastroenterol 2014; 20(36): 13139-13145
URL: https://www.wjgnet.com/1007-9327/full/v20/i36/13139.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i36.13139